Health Canada's Food Directorate completed a safety assessment of L-alpha-glycerylphosphorylcholine (also called alpha GPC or choline alfoscerate) for use in supplemented foods.
Health Canada published a Notice of proposal to enable the use of L-alpha-glycerylphosphorylcholine as a supplemental ingredient in foods (NOP/ADP SI-006) on April 17, 2023. The proposal was open to the public for comment for 75 days. A summary of the comments that were provided during this period with any applicable responses is available in the information document referenced below.
The results of this safety assessment support the safety of L-alpha-glycerylphosphorylcholine as a source of supplemental choline for use in supplemented foods. Consequently, Health Canada has enabled the use of L-alpha-glycerylphosphorylcholine described in the information document below by modifying the List of permitted supplemental ingredients, effective September 20, 2023.